Korean J Gastrointest Endosc > Volume 8(2); 1988 > Article

Korean Journal of Gastrointestinal Endoscopy 1988;8(2): 121-126.

상부소화관 내시경검사가 혈중 Catecholamine 농도에 미치는 영향에 관한 연구 ( Response of the Sympathetic System During and After Fiberoptic Gastroscopy )

윤세옥, 김은주, 고완, 김선우 (Sei Ok Yoon, Eun Joo Kim, Wan Ko and Sun Woo Kim)

Abstract

Cardiovascular changes induced by a variety of physiological, surgical or emotional stresses are associated with increased sympathetic nervous system activtity. Sympathetic stimulation lowers the ventricular resistance in patients with ischemic heart disease. Thus sympathoadrenal aetivation may play role in sudden cardiac death. We measured the catecholamine levels just before and after fiberoptic gastroscopy, The results were as follows: 1) Though there was no statistical significance, plama catecholamine levels tends to increase during and after fiberoptic gastroscopy. 2) Significant changes in mean blood pressure did not occur during and after fiberoptic gastroscopy. 3) Before fiberoptic gastroscopy, norepinephrine level of three hypertensive patients were lower than the levels of studied patients, But during and after fiberoptic gastroacopy, norepinephrine level increased by 3 times. 4) The highest norepinephrine level was 847 pg/ml and epinephrine level was 110 pg/ml. Though sympathetic response was enhanced by fiberoptic gastroscopy, norepinephrine level did not increase up to the level shown in myocardial infarction or severe exercise.