Korean J Gastrointest Endosc > Volume 30(3); 2005 > Article
Korean Journal of Gastrointestinal Endoscopy 2005;30(3): 173-177.
직장에 발생한 출혈성 위장관 간질종양
신정아·김성준·신원창·이진호·최원충·김관엽·정명자*·임성직
인제대학교 의과대학 상계백병원 내과학교실, *방사선학교실, 병리학교실
A Case of Rectal Gastrointestinal Stromal Tumor with Bleeding
Jeong Ah Shin, M.D., Seong Jun Kim, M.D., Won Chang Shin, M.D., Jin Ho Lee, M.D., Won Choong Choi, M.D., Kwan Yeop Kim, M.D., Myeong Ja Jeong, M.D.* and Sung-Jig Lim, M.D.
Departments of Internal Medicine, *Radiology and Pathology, Inje University College of Medicine, Seoul, Korea
Abstract
Gastrointestinal stromal tumors (GIST), although uncommon mesenchymal tumors of the gastrointestinal tract, are occasionally encountered on endoscopic examination. GIST can be found all gastrointestinal tract, but rare in the rectum. We report a 72-year-old woman presented with intermittent bloody stool for a year. On rectal examination, a firm fixed mass was felt on the anterior wall of the rectum. Computed tomography revealed the 4.8⁓4.5 cm sized exophytic and centrally depressed mass on the rectum without the evidence of adjacent organ invasion or metastasis. On colonoscopic examination, there was a round elevated lesion having central ulcer with adherent blood clots. Endoscopic deep biopsy examination revealed a submucosal tumor consisting of spindle cells with elongated cigar-shaped nuclei arranged in fascicles and whorls. Mitotic counts were fewer than 5 per 50 high-power fields. The tumor cells were positive for KIT and CD34 immunohistostaining and negative for SMA. Local excision recommended, but the patient discharged against the advice. Korean J Gastrointest Endosc 2005;30:173⁣177)
Key Words: GIST, Rectum, KIT, CD34
주요어: GIST, 직장, KIT, CD34
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