Korean J Gastrointest Endosc > Volume 30(6); 2005 > Article
Korean Journal of Gastrointestinal Endoscopy 2005;30(6): 291-296.
체부 마마양 위염에서 림프구성 위염의 빈도와 임상상
가톨릭대학교 의과대학 내과학교실
Incidence of Lymphocytic Gastritis in Endoscopic Corporeal Varioliform Gastritis
Hae Won Han, M.D., In Seok Lee, M.D., Nak Gi Kwan, M.D., Jae Myung Park, M.D., Jung Hwan Oh, M.D., Yu Kyung Cho, M.D., Sang Woo Kim, M.D., Myung-Gyu Choi, M.D. and In-Sik Chung, M.D.
Department of Internal Medicine, The Catholic University of Korea College of Medicine, Seoul, Korea

Lymphocytic gastritis is characterised by the accumulation of small lymphocytes in the surface and foveolar epithelium. It is a common finding in a subtype of gastritis characterized by the presence of nodules and erosions in the body, relative to which the antrum was spared-'varioliform gastritis'. Lymphocytic gastritis usually follows a chronic course and presents severe clinical symptoms including hypoproteinemia. The aim of this study was to investigate the incidence and clinical manifestations of lymphocytic gastritis in patients who showed endoscopic apprearance of enlarged folds, erosions, and aphthoid nodules in the body.
Materials and Methods
: The clinical and histological findings of varioliform gastritis with presence of nodules and erosions in the body were analyzed. The ratio of 25 lymphocytes/100 epithelial cell was used as the criteria for the diagnosis of lymphocytic gastritis in the study.
Twenty nine cases were classified as varioliform gastritis (there were 20 men/9 women and average age was 48.9 years). Among the 29 varioliform gastritis, 9 corresponded to lymphocytic gastritis. H. pylori infection rate was 44% (4/9) in lymphocytic gastritis and 65% in non lymphocytic gastritis. There was no difference in H. pylori infection rate between the lymphocytic gastritis and non lymphocytic gastritis. Clinical laboratory findings of lymphocytic gastritis were normal. The patients with lymphocytic gastritis had absence of mild degree of symptoms. Among 4 patients with follow-up endoscopy, erosions in body were completely disappreared in 3 patients.
Lymphocytic gastritis occurred in about 30% of patients with varioliform gastritis. Most patients with lymphocytic gastritis had no symptoms or only mild symptoms and had no significant abnormality in clinical or laboratory finding. (Korean J Gastrointest Endosc 2005;30:291⁣296)
Key Words: Lymphocytic gastritis, Varioliform gastritis
주요어: 림프구성 위염, 체부 마마양 위염
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