Korean J Gastrointest Endosc > Volume 31(3); 2005 > Article
Korean Journal of Gastrointestinal Endoscopy 2005;31(3): 180-184.
Infliximab으로 호전된 Cap Polyposis 1예
김동일·진윤태·박상훈·천황래·백창원·김용식·전훈재·이홍식·엄순호·최재현·김창덕·류호상·신봉경*·현진해
고려대학교 의과대학 내과학교실, 소화기연구소, *병리학교실
A Case of Cap Polyposis Successfully Managed with Infliximab
Dong Il Kim, M.D., Yoon Tae Jeen, M.D., Sang Hoon Park, M.D., Hwang Rae Chun, M.D., Chang Won Baeck, M.D., Yong Sik Kim, M.D., Hoon Jai Chun, M.D., Hong Sik Lee, M.D., Soon Ho Um, M.D., Jai Hyun Choi, M.D., Chang Duck Kim, M.D., Ho Sang Ryu, M.D., Bong Ky
Departments of Internal Medicine, Institute of Digestive Disease and Nutrition, *Pathology, Korea University College of Medicine, Seoul, Korea
Abstract
Cap polyposis is a rare disorder characterized by bloody, mucoid diarrhea with rectosigmoid polyps covered by a cap of fibrinopurulent exudate. The etiology and pathogenesis of cap polyposis is unknown, and no specific treatment has been established. Drug therapies are usually unsuccessful. Patients with a solitary cap polyp respond well to endoscopic polypectomy, while patients with multiple polyps and concurrent anorectal pathology require surgical resection. However, rapid recurrence has been described after a limited surgical resection, and this necessitates panproctocolectomy. We report a case of a 58-year-old female diagnosed as cap polyposis on rectum with similar clinical and endoscopic features of pseudomenbranous colitis successfully treated with infliximab (murine chimeric monoclonal antibody to TNF-α). (Korean J Gastrointest Endosc 2005;31:180⁣184)
Key Words: Cap polyposis, Infliximab, Pseudomembranous colitis
주요어: 모자용종증, Infliximab, 위막성대장염
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