Korean J Gastrointest Endosc > Volume 32(4); 2006 > Article
Korean Journal of Gastrointestinal Endoscopy 2006;32(4): 278-282.
비스테로이드성 소염진통제의 단기간 사용 후 발생한 십이지장 궤양 협착 1예
이화여자대학교 의과대학 내과학교실, 의과학연구소
A Case of Duodenal Obstruction Induced by the Short-term Use of a Nonsteroidal Anti-inflammatory Drug
Ji Hyun Song, M.D., Ki Nam Shim, M.D., Hyun Joo Song, M.D., Hee Jung Oh, M.D., Kum Hei Ryu, M.D., Hye Jung Yeom, M.D., Seong-Eun Kim, M.D., Tae Hun Kim, M.D., Hye Kyung Jung, M.D., Sung-Ae Jung, M.D., Kwon Yoo, M.D. and Il Hwan Moon, M.D.
Department of Internal Medicine, Ewha Medical Research Institute, Ewha Womans University College of Medicine, Seoul, Korea
Giant duodenal ulcer can be defined as a variant of peptic ulceration that exceeds 2 cm at the greatest diameter. The high mortality and morbidity of giant duodenal ulcer are directly related to the resultant perforation, obstruction and massive hemorrhage. The patient usually has a long history of an inadequately treated or neglected peptic ulcer, but this malady is rarely induced by nonsteroidal anti- inflammatory drugs (NSAIDs). A 60-year-old man was referred to us due to epigastric pain. He underwent appendectomy 1 week ago, and he was administered ketorolac (tarasyn) for 5 days to control the postoperative pain. Esophagogastroduodenos copy (EGD) revealed a giant duodenal ulcer encircling the lumen from the pylorus to the postbulbar portion of the duodenum, and he was then treated with proton pump inhibitor. Two weeks later, the follow-up EGD showed complete duodenal obstruction at the bulb. He was treated by laparoscopic gastrojejunostomy. We report here on this case of duodenal obstruction that was induced by the short-term use of NSAIDs. (Korean J Gastrointest Endosc 2006;32:278⁣282)
Key Words: NSAIDs, Duodenal obstruction
주요어: 비스테로이드성 소염진통제, 십이지장 궤양 협착
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