Korean J Gastrointest Endosc > Volume 33(2); 2006 > Article
Korean Journal of Gastrointestinal Endoscopy 2006;33(2): 110-115.
혈변으로 발견된 직장 간질종양 1예
최은영·길 호·전원중·박선미·김석형*·박길선·윤세진
충북대학교 의과대학 내과학교실, *병리학교실, 방사선과학교실
A Case of Rectal Gastrointestinal Stromal Tumor (GIST) Presenting with Hematochezia
Eun Young Choi, M.D., Ho Kil, M.D., Won Joong Jeon, M.D., Seon Mee Park, M.D. Seok Hyung Kim, M.D.*, Kil Sun Park, M.D. and Sei Jin Youn, M.D.
Departments of Internal Medicine, *Pathology and Radiology, Chungbuk National University College of Medicine, Cheongju, Korea
Gastrointestinal stromal tumors (GIST) are the most common mesenchymal neoplasms affecting the gastrointestinal tract. The main sites for GIST are the stomach and small intestine but they can also occur in the rectum, albeit rarely. We report a 58-year-old woman who presented with hematochezia. Endoscopically, a submucosal tumor with mucosal ulceration was located approximately 2 cm from the anal verge. The pelvic CT and MRI scanning findings demonstrated a large low-density lesion with intraluminal growth from the lower rectum and an absence of tumor infiltrations to other organs. The patient underwent an abdominoperineal resection of the rectum. A histopathological examination showed fascicular proliferation of spindle shaped cells. The mitotic rate was more than 30 mitotic figures per 50 high-power fields. A immunohistochemical examination revealed most of the tumor cells to be positive for the c-kit protein, CD34 and SMA (α-smooth muscle action). The tumor was diagnosed as a GIST of the rectum. (Korean J Gastrointest Endosc 2006;33:110⁣115)
Key Words: Gastrointestinal stromal tumor (GIST), Rectum, Hematochezia
주요어: 간질종양, 직장, 출혈
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