Korean J Gastrointest Endosc > Volume 33(3); 2006 > Article
Korean Journal of Gastrointestinal Endoscopy 2006;33(3): 135-139.
단일 기관에서 경험한 심재성 낭종성 위염의 임상상
*가톨릭대학교 의과대학 내과학교실, 충남대학교 의과대학 내과학교실, 병리학교실, 진단방사선학교실, §외과학교실
Our Experience of Gastritis Cystica Profunda Cases and Its Clinical Study
Yeon Soo Kim, M.D.*, Won Seok Heo, M.D., Kyung Hoon Chae, M.D., Jae Hoon Jung, M.D., Youn Se Gang, M.D., Seok Hyun Kim, M.D., Jae Koo Seong, M.D., Byung Seok Lee, M.D., Hyun Yong Jeong, M.D., Kyu Sang Song, M.D., Kyung Sook Shin, M.D.
*Department of Internal Medicine, The Catholic University of Korea College of Medicine, Seoul, Departments of Internal Medicine, Pathology, Radiology and §Surgery, Chungnam National University College of Medicine, Daejeon, Korea

Gastritis cystica profunda (GCP) is a rare disease that is characterized by a hyperplastic and cystic dilatation of the pseudopyloric gland with submucosal invasion. GCP is regarded as a benign lesion. However, there is some controversy regarding its malignant potential. This study reviewed the clinical features and association with malignancy.
From January 2001 to June 2005, 1,010 cases of resected and 1,228 cases of an endoscopic mucosal resection or polypectomy were examined.
Thirty-nine cases (1.7%) were confirmed pathologically and were not associated with prior gastric surgery mostly. The mean age was 60.0±11.4 years old and there were 29 male patients. The body was most commonly located on the longitudinal axis (57.1%). Eleven cases (28.2%) were not associated any other gastric lesion, the majority of which were the polypoid type (82.0%). However, two cases were found as a hypertrophic mucosal fold, and a submucosal tumor, respectively. Seventeen cases (43.6%) were associated with early gastric cancer.
Despite its rarity, GCP should be considered when an endoscopically polypoid lesion or submucosal tumor (SMT) is found. Because of its association with early gastric cancer or adenoma, more study will be needed to examine the relationship between GCP and gastric carcinogenesis. (Korean J Gastrointest Endosc 2006;33:135⁣139)
Key Words: Gastritis cystica profunda, Carcinogenesis
주요어: 심재성 낭종성 위염, 악성화
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