Korean J Gastrointest Endosc > Volume 33(4); 2006 > Article
Korean Journal of Gastrointestinal Endoscopy 2006;33(4): 230-234.
위점막 석회침착증 2예
대구파티마병원 소화기내과, *병리과
Two Cases of Gastric Mucosal Calcinosis
Ju Chun Yeo, M.D., Dong Uk Ju, M.D., Se Young Lee, M.D., Sung Woo Eum, M.D., Jai Hyun Lee, M.D., Se Hwan Kim, M.D., Chang Keun Park, M.D., Seung Yup Lee, M.D., Hyun Soo Kim, M.D. and Mi Jin Koo, M.D.*
Departments of Internal Medicine and *Pathology, Daegu Fatima Hospital, Daegu, Korea
Gastric mucosal calcinosis (GMC) is a very rare condition that is characterized by the nodular deposition of calcium salts in the gastric mucosa. It has been associated with renal failure, gastric cancer, ingestion of aluminum- containing antacids and the use of sucralfate in organ transplant patients. The etiology of this condition is uncertain, but several theories have been proposed; the condition is due secondarily to hyperparathyroidism in renal failure and to the alkalinization of the gastric mucosa. We report here on two patients who had long- term use of bismuth and/or aluminum-containing antacids to treat their gastro-esophageal reflux symptoms. The esophagogastroduodenoscopy revealed acute gastritis patterns, and GMC was confirmed histologically with biopsy. When one patient stopped ingesting bismuth-containing antacid solution, the follow-up esophagogastroduodenoscopy and the biopsy revealed a completely improved state. We report here on these interesting cases and we include a brief review of the literature. (Korean J Gastrointest Endosc 2006;33:230⁣234)
Key Words: Gastric mucosal calcinosis, Bismuth, Aluminum-containing antacids
주요어: 위점막 석회침착증, 비스무트, 알루미늄 제산제
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