Korean J Gastrointest Endosc > Volume 33(5); 2006 > Article
Korean Journal of Gastrointestinal Endoscopy 2006;33(5): 326-331.
다발성 내분비 종양과 동반된 췌장의 내, 외분비 암 1예
한양대학교 의과대학 내과학교실
A Case of Pancreatic Endocrine and Exocrine Tumor with MEN Type I
Oh Wan Kwon, M.D., Ho Soon Choi, M.D., Jee Hyun Kim, M.D., Won Moon, M.D., Jung Mi Kim, M.D., Dong Hee Koh, M.D., Hang Rak Lee, M.D., Oh Young Lee, M.D., Byung Chul Youn, M.D., Joon Soo Ham, M.D., Dong Hoo Lee, M.D., Min Ho Lee, M.D. and Choon Suhk Kee, M
Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea
An acinar cell carcinoma of the exocrine pancreas is a rare tumor with reported a incidence of 1% to 2% of pancreatic carcinomas. Cases of acinar cell carcinomas with amphicrine features have been reported in recent decades. However, there are no reports of two simultaneous pancreatic masses: an endocrine tumor and, an exocrine tumor. We encountered a 59-year-old female patient presenting with abdominal pain and melena. The acinar cell carcinoma was a 1⁓1 cm-sized round solid mass in the head of the pancreas. The islet tumor was a 2.5⁓1.5 cm-sized round mass in the body of the pancreas. The endocrine tumor was nonfunctioning. Melena resulted from the hemosuccus pancreaticus due to a ductal invasion of the acinar cell carcinoma. The patient had a parathyroid adenoma with hyperparathyroidism. Therefore, both the islet tumor and parathyroid adenoma with hyperparathyroidism were strongly suggestive of a MEN I. (Korean J Gastrointest Endosc 2006;33:326⁣332)
Key Words: Carcinoma, Acinar cell, Islet tumor, Hemosuccus pancreaticus, MEN type I
주요어: 선방세포암, 소도세포암, 췌관출혈, 다발성 내분비 종양
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