Korean J Gastrointest Endosc > Volume 35(2); 2007 > Article
Korean Journal of Gastrointestinal Endoscopy 2007;35(2): 110-115.
하부위장관 대량 출혈로 발현한 거대세포바이러스 대장염 2예
이수연·최창환·이현웅·도미영·이승현·허 채·김석원·김형준·장세경·이태진*·오화은
중앙대학교 의과대학 내과학교실, *병리학교실, 관동대학교 의과대학 병리학교실
Acute Cytomegalovirus Proctocolitis Presenting with Massive Lower Gastrointestinal Bleeding
Su Yeon Rhie, M.D., Chang Hwan Choi, M.D., Hyun Woong Lee, M.D., Mi Young Do, M.D., Seong Hyun Lee, M.D., Chae Heo, M.D., Suk Won Kim, M.D., Hyung Joon Kim, M.D., Sae Kyung Chang, M.D., Tae Jin Lee, M.D.* and Hwa Eun Oh, M.D.
Departments of Internal Medicine and *Pathology, Chung-ang University College of Medicine, Seoul, Department of Pathology, Kwandong University College of Medicine, Goyang, Korea
Abstract
Cytomegalovirus (CMV) colitis usually affects immunosuppressed patients. However, CMV colitis may also affect patients with a debilitation caused by a severe illness or affect patients that have a specific physiological status (old age, pregnancy). Clinically, patients with CMV colitis most commonly present with abdominal pain, diarrhea, and gastrointestinal bleeding. The diagnosis of CMV colitis usually requires a biopsy of mucosal tissue. The characteristic finding on biopsy reveals CMV inclusion bodies. CMV colitis can be successfully treated with ganciclovir. We report two cases of CMV proctocolitis in elderly patients with chronic diseases that presented with massive lower gastrointestinal bleeding due to multiple rectal ulcerations. A pathological examination showed CMV inclusion bodies. CMV colitis should be considered in the differential diagnosis of patients with massive rectal ulcer bleeding when other causes fail to explain the course of the disease.
Key Words: Cytomegalovirus, Colitis, Bleeding
주요어: 거대세포바이러스, 대장염, 출혈
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