Korean J Gastrointest Endosc > Volume 35(3); 2007 > Article
Korean Journal of Gastrointestinal Endoscopy 2007;35(3): 140-145.
상부 위장관 양성 중간엽종양의 내시경 초음파 검사를 이용한 추적관찰
순천향대학교 의과대학 소화기연구소 소화기병센터
The Endoscopic Ultrasonographic Survey of Benign Mesenchymal Tumor in Upper Gastrointestinal Tract
Soo Jung Lee, M.D., Jin Oh Kim, M.D., Soo Hoon Eun, M.D., Ik Sung Choi, M.D., In Seop Jung, M.D., Bong Min Ko, M.D., Su Jin Hong, M.D., Chang Beom Ryu, M.D., Joo Young Cho, M.D., Joon Seong Lee, M.D., Moon Sung Lee, M.D., So Young Jin, M.D., Chan Sup Shim
Institute for Digestive Research, Digestive Disease Center, SoonChunHyang University College of Medicine, Seoul, Korea

A gastrointestinal mesenchymal tumor contains a leiomyoma and gastrointestinal stromal tumor (GIST). The natural course can vary according to the histology and other characteristics. This study evaluated the natural course of a benign mesenchymal tumor in the upper gastrointestinal tract using endoscopic ultrasonography (EUS).
Submucosal mesenchymal tumors are considered benign according to the following criteria of EUS: 1) the tumor originates from the muscularis mucosa or muscularis propria; 2) is well demarcated, homogenous and hypoechoic; and 3) has a regular surface. In this study, the changes of size, internal echo pattern and marginal regularity were evaluated retrospectively in 26 lesions that all were < 3 cm and were followed up for more than 2 years.
The average size of the tumors on EUS was 11.5 mm. The mean follow-up period was 47.4 months. The follow-up EUS revealed no change in echo features in any patient. In only one patient, the size of the tumor increased from 26 to 34 mm without a change in the internal echo or marginal regularity after 24 months. This patient underwent a laparoscopic gastric wedge resection. The pathologic diagnosis was a leiomyoma.
Most small submucosal tumors that are compatible with the EUS criteria of a benign GIST/ leiomyoma do not change over a period of 24 months, and the EUS criteria are effective in diagnosing benign GISTs/leiomyomas. A benign GIST/leiomyoma at EUS might be followed up by EUS at an interval of 2 years. (Korean J Gastrointest Endosc 2007;35:140-145)
Key Words: Endoscopic ultrasonography, Benign mesenchymal tumor, Gastrointestinal stromal tumor, Leiomyoma
주요어: 내시경 초음파 검사, 양성 중간엽종양, 위장관 간질종양, 평활근종
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