Korean J Gastrointest Endosc > Volume 36(4); 2008 > Article
Korean Journal of Gastrointestinal Endoscopy 2008;36(4): 238-241.
직장 용종으로 나타난 유육종증 1예
연세대학교 의과대학 내과학교실, *소화기병연구소, 병리학교실
A Case of Sarcoidosis Presenting as a Rectal Polyp
Wonseok Kang, M.D., Beom Kyung Kim, M.D., Min Ju Kim, M.D., Jae Hee Cheon, M.D.*, Yong Chan Lee, M.D.*, Won Ho Kim, M.D.* and Sang Kil Lee, M.D.*
Departments of Internal Medicine, *Institute of Gastroenterology and Pathology,Yonsei University College of Medicine, Seoul, Korea
Sarcoidosis is a multi-systemic syndrome with an unknown etiology that is characterized by the formation of multiple non-caseating granulomas that disrupts the architecture and function of the tissues. A 58-year-old woman was referred for a skin rash and papules. No specific findings were observed on the initial skin biopsy. On gastroscopy and colonoscopy, gastric erosion and rectal polyp were noted. The rectal biopsy revealed non-caseating granulomas without acid-fast bacilli, indicating a differential diagnosis of Crohn's disease and other granulomatous diseases. A repeat skin biopsy of the papular lesion showed non-caseating granulomas that was consistent with sarcoidosis. The chest x-ray and computed tomography (CT) revealed cardiomegaly without hilar lymphadenopathy. The serum angiotensin converting enzyme level was 122 U/L (normal: 8∼52 U/L) with normal liver chemistry as well as normal electrolyte, serum calcium and c-reactive protein levels. Finally, the patient was diagnosed with sarcoidosis with rectal involvement. We report this rare case of sarcoidosis that presented as a rectal polyp. (Korean J Gastrointest Endosc 2008;36:238-241)
Key Words: Sarcoidosis, Rectum, Polyps
주요어: 유육종증, 직장, 용종
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