Crohn's disease is a chronic intestinal inflammation and its etiology and pathogenesis have not been defined. Clinical manifestations of Crohn's disease involve abdominal pain, diarrhea, weight loss, intestinal stenosis, presence of fistulas and gastrointestinal hemorrhage. Crohn's disease is also associated with a variety of extraintestinal manifestations such as ankylosing spondylitis, uveitis and primary sclerosing cholangitis. We report a case of Crohn's disease associated with noncaseating granulomatous liver disease that is rare in Korea. (Korean J Gastrointest Endosc 2008;36:298-301)