Korean J Gastrointest Endosc > Volume 37(1); 2008 > Article
Korean Journal of Gastrointestinal Endoscopy 2008;37(1): 55-60.
대장내시경 전처치제로 Sodium Phosphate 복용 후 발생한 경련 및 의식 저하를 동반한 저나트륨혈증 2예
이화여자대학교 의과대학 내과학교실, 의과학연구소
Hyponatremia with Seizure and Mental Change after Oral Sodium Phosphate Bowel Preparation: Report of Two Cases
Su Jung Baik, M.D., Ki-Nam Shim, M.D., Youn Ju Na, M.D., Min-Jung Kang, M.D., Ji Min Jung, M.D., Sung-Ae Jung, M.D., Kwon Yoo, M.D. and Seung-Jung Kim, M.D.
Department of Internal Medicine, Ewha Medical Research Institute, Ewha Womans University School of Medicine, Seoul, Korea
Oral sodium phosphate is known to be safe and it is widely used as a colon cleansing agent for colonoscopy. Yet several complicated cases with the development of electrolyte imbalance have been reported. We report here on 2 interesting cases: after administration of oral sodium phosphate, one patient presented with hyponatremia (Na, 122 mEq/L) with seizure and the other patient presented with hyponatremia (Na, 120 mEq/L) with a confused mentality. Brain imaging and electroencephalography showed no evidence of other causes for the seizure and mental change. We report here on two cases of hyponatremia with neurologic side effects, and this was all caused by oral sodium phosphate. We also include a review of the relevant literature. (Korean J Gastrointest Endosc 2008; 37:55-60)
Key Words: Sodium phosphate, Hyponatremia, Seizure
주요어: Sodium phosphate, 저나트륨혈증, 경련
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