Korean J Gastrointest Endosc > Volume 38(3); 2009 > Article
Korean Journal of Gastrointestinal Endoscopy 2009;38(3): 166-170.
대장 침범이 확인된 랑게르한스 세포 조직구증 1예
울산대학교 의과대학 서울아산병원 소화기내과
A Case of Langerhans Cell Histiocytosis That Involved the Colon
Sang Jin Lee, M.D., Kyung-Jo Kim, M.D., Soon Man Yoon, M.D., Byong Duk Ye, M.D., Jeong-Sik Byeon, M.D., Seung-Jae Myung, M.D., Suk-Kyun Yang, M.D. and Jin-Ho Kim, M.D.
Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea
A 34-year-old man was referred to our department for evaluation of his elevated liver function test. He was diagnosed with Langerhans cell histiocytosis 7 years ago because of recurrent pneumothorax. A CT scan showed multifocal intrahepatic duct dilatation with soft tissue infiltration in the right lobe of the liver. An ERCP showed diffuse multifocal strictures of the intrahepatic duct intervening among the normal segments of the duct. A percutaneous needle biopsy of the liver disclosed ductular proliferation, inflammatory cell infiltration and focal cholestasis. Therefore, he was diagnosed with sclerosing cholangitis. He underwent colonoscopy to evaluate for the possibility of ulcerative colitis. The colonoscopy showed erosions and erythema on the mucosa of the appendiceal orifice, another site of erosion at 35 cm from the anal verge and multiple 3~8 mm sized sessile polyps. Biopsies of the colon mucosa disclosed an infiltration of Langerhans cell histiocytosis. We report here on a very rare case of colon involvement of Langerhans cell histiocytosis. (Korean J Gastrointest Endosc 2009;38:166-170)
Key Words: Langerhans cell histiocytosis, Sclerosing cholangitis, Colon
주요어: 랑게르한스 세포 조직구증, 경화성 담관염, 대장
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