Korean J Gastrointest Endosc > Volume 38(4); 2009 > Article
Korean Journal of Gastrointestinal Endoscopy 2009;38(4): 237-241.
호중구감소 환자에서 발생한 침습 칸디다 대장염 1예
울산대학교 의과대학 강릉아산병원 내과학교실, *진단병리학교실, 순천향대학교 의과대학 내과학교실
A Case of Invasive Candidal Colitis in a Neutropenic Patient
Se Hyung Lee, M.D., Yun Ho Kong, M.D., Koon Hee Han, M.D., Young Don Kim, M.D., Woo Jin Jeong, M.D., Dae Woon Eom, M.D.*, Ji Hoon Kim, M.D. and Gab Jin Cheon, M.D.
Departments of Internal Medicine and *Pathology, Ulsan University College of Medicine, Gangneung Asan Hospital, Gangneung, Department of Internal Medicine, Soonchunhyang University College of Medicine, Asan, Korea
The candida species are considered as resident microflora in healthy persons. Yet in immunocompromised patients, candida can cause opportunistic invasive fungal infections. A 67-year-old woman presented to the hospital with abdominal pain and diarrhea. On admission, the laboratory studies revealed profound neutropenia, and the abdominal computed tomography showed thickened walls of the ascending colon and terminal ileum. The patient's fever and clinical symptoms continued for 5 days in spite of the empirical antibiotic therapy. We performed colonoscopy and obtained biopsy specimens at the ulcer lesions of the ascending colon and terminal ileum. The histology showed that candida hyphae had invaded to the lamina propria of the colonic mucosa. After antifungal treatment, her clinical symptoms subsided and the follow-up colonoscopic findings showed improvement. Therefore, we suggest that invasive candidal colitis should be considered in the differential diagnosis of neutropenic enterocolitis. (Korean J Gastrointest Endosc 2009;38:237-241)
Key Words: Candidal colitis, Neutropenia
주요어: 칸디다 대장염, 호중구감소
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