Korean J Gastrointest Endosc > Volume 38(4); 2009 > Article
Korean Journal of Gastrointestinal Endoscopy 2009;38(4): 188-192.
내시경 겸자 생검과 내시경 점막하 박리술 후 획득된 조직의 병리학적 차이에 대한 고찰
김영대ㆍ조주영ㆍ정인섭ㆍ고봉민ㆍ홍수진ㆍ유창범ㆍ김진오ㆍ이준성ㆍ이문성ㆍ진소영*ㆍ심찬섭ㆍ김부성
순천향대학교 의과대학 내과학교실, 소화기 연구소, *병리학교실
Comparison of Endoscopic Forcep Biopsy and the Histopathologic Diagnosis after Endoscopic Submucosal Dissection
Young Dae Kim, M.D., Joo Young Cho, M.D., In Seop Jung, M.D., Bong Min Koh, M.D., Su Jin Hong, M.D., Chang Beom Ryu, M.D., Jin Oh Kim, M.D., Joon Seong Lee, M.D., Moon Sung Lee, M.D., So Young Jin, M.D.*, Chan Sup Shim, M.D. and Boo Sung Kim, M.D.
Departments of Internal Medicine and *Anatomy Pathology, Institute for Digestive Research, Digestive Disease Center, Soonchunhyang University College of Medicine, Seoul, Korea
Abstract

Background/Aims:
The discrepancy of the histopathological diagnosis between endoscopic forcep biopsy, surgery and endoscopic mucosal resection (EMR), has been reported on in a previous study. We compared the results of endoscopic forcep biopsy and the histopathologic diagnosis after performing endoscopic submucosal dissection (ESD).
Methods:
We retrospectively reviewed 434 lesions for which we were able to compare the post-ESD histopathologic results with the endoscopic biopsy.
Results:
1) Of the 14 lesions that showed chronic gastritis or atypia by endoscopic biopsy, 9 were diagnosed with carcinoma in situ or adenocarcinoma after ESD. 2) fifty one of 141 lesions that showed low grade dysplasia on the endoscopic biopsy were diagnosed with carcinoma in situ or adenocarcinoma after ESD. 3) Of the 60 lesions that showed high grade dysplasia on the endoscopic biopsy, 46 were diagnosis with carcinoma in situ or adenocarcinoma after ESD.
Conclusions:
The discrepancy of the histopathological diagnosis was found between ESD and forcep biopsy. In light of these results, if a lesion that is suspected to be EGC, although it is not diagnosed by endoscopic biopsy, then it should be confirmed by ESD. (Korean J Gastrointest Endosc 2009;38:188-192)
Key Words: Endoscopic forcep biopsy, Endoscopic submucosal dissection, Early gastric cancer, Gastric adenoma
주요어: 내시경 겸자 생검, 내시경 점막하 박리술, 조기 위암, 위선종
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