Korean J Gastrointest Endosc > Volume 38(5); 2009 > Article
Korean Journal of Gastrointestinal Endoscopy 2009;38(5): 284-287.
위 점막하 종양으로 발현된 황색육아종성 염증 1예
박민경ㆍ양홍준ㆍ임창훈ㆍ김태호ㆍ김창환ㆍ김진아ㆍ김 욱*ㆍ한석원
가톨릭대학교 의과대학 내과학교실, *외과학교실, 병리학교실
Xanthogranulomatous Inflammation Presenting as a Submucosal Mass of the Stomach
Min Kyoung Park, M.D., Hong Jun Yang, M.D., Chang Hoon Lim, M.D., Tae Ho Kim, M.D., Chang Whan Kim, M.D., Jean A Kim, M.D., Wook Kim, M.D.* and Sok Won Han, M.D.
Departments of Internal Medicine, *Surgery and Pathology, College of Medicine, The Catholic University of Korea, Seoul, Korea
Xanthogranulomatous inflammation is a rare chronic inflammatory condition that is characterized by aggregation of lipid-laden foamy macrophages (xanthoma cells). Although the precise pathogenesis of xanthogranulomatous inflammation is not well understood, various mechanisms have been proposed, including chronic recurrent infection, the presence of gallstones, immunologic disorders and defective lipid transport. This disease entity is well recognized in the kidney and gallbladder, yet involvement of the gastrointestinal tract is extremely rare and the involvement of both the stomach and colon has never been reported on. A coexisting malignancy rarely has been reported in a patient with xanthogranulomatous inflammation. This might present as an inflammatory mass-like lesion with infiltration to the surrounding tissues, and so this often mimics advanced cancer. Therefore, a surgical operation together with careful pathological evaluation is required for making the precise diagnosis. We herein report on a case of xanthogranulomatous inflammation that presented as a submucosal mass in the stomach which was a huge irregular mass involving transverse colon. (Korean J Gastrointest Endosc 2009;38:284-287)
Key Words: Xanthogranulomatous inflammation, Stomach submucosal mass, Colonic involvement
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