Korean J Gastrointest Endosc > Volume 39(3); 2009 > Article
Korean Journal of Gastrointestinal Endoscopy 2009;39(3): 169-171.
Polyethylene Glycol을 이용한 대장정결 후 발생한 급성 저나트륨 뇌병증 1예
허 채ㆍ오형철ㆍ김정욱ㆍ김재규
중앙대학교 의과대학 내과학교실
Acute Hyponatremic Encephalopathy after Ingestion of Polyethylene Glycol Solution before Colonoscopy
Chae Heo, M.D., Hyoung Chul Oh, M.D., Jeong Wook Kim, M.D. and Jae Gyu Kim, M.D.
Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Korea
Abstract
Preparation for colonoscopy involves a thorough cleansing of the large bowel. Cleansing is performed using several methods, including ingestion of 4 liters of polyethylene glycol solution. However, these methods can induce hyponatremia by various mechanisms. Severe or rapidly progressing hyponatremia can result in the swelling of the brain, and the symptoms of hyponatremia are mainly neurological. Recently, we encountered a 41-year-old woman who developed acute hyponatremia with encephalopathy after undergoing bowel preparation for colonoscopy. She presented with general weakness, nausea, headache, agitation, delusions, and slurred speech one day after the ingestion of polyethylene glycol solution. Her serum sodium level was very low (110 to 115 mEq/L). Her symptoms pertaining to hyponatremia continued to persist for more than 2 days despite continuous intravenous administration of hypertonic saline for the correction of hyponatremia. (Korean J Gastrointest Endosc 2009;39:169-171)
Key Words: Hyponatremia, Colonoscopy, Polyethylene glycol
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