Korean J Gastrointest Endosc > Volume 39(5); 2009 > Article
Korean Journal of Gastrointestinal Endoscopy 2009;39(5): 313-318.
위배출시간의 지연을 동반한 호산구성 위염 1예
배선윤ㆍ이 혁ㆍ정호중ㆍ김미연ㆍ이미래
성균관대학교 의과대학 삼성서울병원 내과학교실
A Case of Eosinophilic Gastritis with Delayed Gastric Emptying
Sun Youn Bae, M.D., Hyuk Lee, M.D., Ho Jung Chung, M.D., Mi Yeon Kim, M.D. and Mi Rae Lee, M.D.
Department of Medicine, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Korea
Abstract
Eosinophilic gastritis is a rare disease that is characterized by eosinophilic infiltration of the bowl wall tissue, and the presentation of symptoms varies depending on the affected site. It is likely that eosinophil-active cytokines play important roles in this disease. A 22-year old man presented with abdominal pain and vomiting. Endoscopic gastric biopsy revealed eosinophilic infiltration, and the serum level of Interleukin (IL)-5 was increased. Gastric emptying was moderately delayed in this patient. The patient was treated with steroid and he showed dramatic clinical improvement with disappearance of the eosinophilic infiltration of the gastric mucosa, normalization of the serum level of IL-5 and improvement of the gastric emptying time. There has been few case reports of eosinophilic gastritis that have described the change of the serum level of cytokines and the gastric emptying. We report here on a case of eosinophilic gastritis and the patient showed elevated serum level of cytokines and delayed gastric emptying. The patient improved after being treated with steroid. (Korean J Gastrointest Endosc 2009; 39:313-318)
Key Words: Eosinophilic gastritis, Cytokines, Gastric emptying
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