Korean J Gastrointest Endosc > Volume 39(5); 2009 > Article
Korean Journal of Gastrointestinal Endoscopy 2009;39(5): 265-270.
대장내시경 전 처치제로서 Sulfate Free Polyethylene Glycol 용액과 Sodium Phosphate 용액의 전향적 비교 분석
인제대학교 의과대학 서울백병원 내과학교실
A Prospective Comparison of Sulfate Free Polyethylene Glycol versus Sodium Phosphate Solution for Precolonoscopic Bowel Preparation
Jin Gook Huh, M.D., You Sun Kim, M.D., Jong Hyeok Park, M.D., Kyung Sun Ok, M.D., Won Cheol Jang, M.D., Tae Yeob Jeong, M.D., Soo Hyung Ryu, M.D., Jung Hwan Lee, M.D. and Jeong Seop Moon, M.D.
Department of Internal Medicine, Seoul Paik Hospital, Inje University College of Medicine, Seoul, Korea

Polyethylene glycol (PEG) solution is commonly used for precolonoscopic preparation because of its safety and effectiveness. Sulfate free PEG (SF-PEG) solution was developed to reduce the salty taste by removing the sodium sulfate. The aim of this study was to compare the efficacy and patient compliance of SF-PEG and sodium phosphate (NaP) solutions for preparing the bowel before colonoscopy.
From February through April in 2007, 534 patients who underwent colonoscopy were prospectively enrolled. The efficacy of bowel cleansing was assessed by a doctor's questionnaire and the patient's compliance was assessed by a patient's questionnaire.
There was no significant difference between the groups for the "stools and fluids" assessment of bowel cleansing (2.07 vs. 2.14, respectively, p=0.149). However, SF-PEG was more effective on the "air bubbles" assessment (1.34 vs. 1.71, respectively, p<0.001) and the overall assessment (0.72 vs. 0.91, respectively, p=0.010) than NaP. The patients preferred SF-PEG rather than NaP for "Taste" (1.34 vs. 2.25, respectively, p=0.148). However, the patients significantly preferred NaP rather than SF-PEG for "Quantity" (2.46 vs. 1.18, respectively, p<0.001).
The SF-PEG solution showed more effectiveness for bowel cleansing as compared to the NaP solution. SF-PEG tastes better than NaP, but patients are still required to consume 4 liters for the standard preparing regimen. (Korean J Gastrointest Endosc 2009;39:265-270)
Key Words: Sulfate free polyethylene glycol, Sodium phosphate, Bowel cleansing, Patient's compliance
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