Korean J Gastrointest Endosc > Volume 39(6); 2009 > Article
Korean Journal of Gastrointestinal Endoscopy 2009;39(6): 329-337.
호산구 식도염
조 윤 주
을지대학교 의과대학 내과학교실
Eosinophilic Esophagitis
Yun Ju Jo, M.D.
Department of Medicine, Eulji University College of Medicine, Seoul, Korea
Abstract
Eosinophilic esophagitis, as a new emerging disease during the last decade, is a clinicopathologic disorder of the esophagus, and it is characterized by dense esophageal eosinophilic infiltrations and typical esophageal symptoms. These patients usually present with dysphagia, food impaction or refractory reflux symptoms, and biopsy of the esophagus shows more than 15 eosinophils per high-power field. The typical findings on endoscopy are linear furrows, ringed esophagus, mucosal nodularities, whitish plaques and/or stricture. It is essential to exclude the known causes of tissue eosinophilia such as gastroesophageal reflux disease, eosinophilic gastroenteritis, infections, drug, hypersensitivity, Crohn's disease or malignancy. The majority of these patients have an atopy or allergic disorders, so other causes of eosinphilia should be evaluated. The therapeutic options include acid suppression, steroids, dietary modification, endoscopic dilatation, etc. Eosinophilic esopahgitis has recently been reported in Korea. Future schematic studies about this new disease are needed. (Korean J Gastrointest Endosc 2009;39:329-337)
Key Words: Eosinophilic esophagitis, Eosinophilia, Dysphagia, Reflux, Refractory esophagitis
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