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Korean J Gastrointest Endosc > Volume 40(2); 2010 > Article
Korean Journal of Gastrointestinal Endoscopy 2010;40(2): 126-129.
소장 캡슐 내시경을 시행한 Cronkhite-Canada 증후군 1예
박 완ㆍ전우규ㆍ이재은ㆍ최원석ㆍ서미혜ㆍ윤민용ㆍ송창석ㆍ김동훈*
성균관대학교 의과대학 강북삼성병원 내과학교실, *해부병리학교실
A Case of Cronkhite-Canada Syndrome Conducted with Capsule Endoscopy of Small Intestine
Wan Park, M.D., Woo Kyu Jeon, M.D., Jae Eun Lee, M.D., Won Suk Choi, M.D., Mi Hae Seo, M.D., Min Yong Yoon, M.D., Chang Seok Song, M.D. and Dong Hun Kim, M.D.*
Departments of Internal Medicine and *Pathology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea
Abstract
Cronkhite-Canada syndrome is a very rare syndrome. This non-familial hamartomatous polyposis syndrome is characterized by multiple polyps on the entire gastrointestinal tract, nail dystrophy, skin pigmentation and systemic alopecia. The courses of this syndrome could be classified into five types according to clinical symptoms; diarrhea, taste disturbance, xerostomia, abdominal pain and alopecia. Cronkhite-Canada syndrome has a high mortality rate up to 45∼60% due to nutritional absorption disturbance, hypoalbuminemia, recurrent infection, sepsis, heart failure and gastrointestinal bleeding. A pathogenesis of Cronkhite-Canada syndrome is still unknown, and only conservative treatment is available. We diagnosed a 55 years-old female with Cronkhite-Canada syndrome based on the clinical symptoms of nail change, taste disturbance and alopecia, and the histologic finding of polyps in the entire gastrointestinal tract; these polyps were found in the stomach, small intestine and large intestine via capsule endoscopy. We report on this case and we review the relevant medical literature. (Korean J Gastrointest Endosc 2010;40:126-129)
Key Words: Cronkhite-Canada syndrome, Polyposis syndrome, Capsule endoscopy
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