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Korean J Gastrointest Endosc > Volume 40(2); 2010 > Article
Korean Journal of Gastrointestinal Endoscopy 2010;40(2): 102-106.
폐선암의 위장, 십이지장 및 대장 원격성 전이 1예
황상연ㆍ안동원ㆍ윤웅재*ㆍ정지봉ㆍ김 원ㆍ정용진ㆍ김병관ㆍ이국래
서울대학교 의과대학 내과학교실, *해부병리학교실
A Case of Gastric, Duodenal and Colonic Metastases from Adenocarcinoma of the Lung
Sang Youn Hwang, M.D., Dong Won Ahn, M.D., Woong Jae Yun, M.D.*, Ji Bong Jeong, M.D., Won Kim, M.D., Yong Jin Jung, M.D., Byeong Gwan Kim, M.D. and Kook Lae Lee, M.D.
Departments of Internal Medicine and *Anatomic Pathology, Seoul National University College of Medicine, Seoul, Korea
Gastrointestinal metastasis of primary lung carcinoma is very rare, although this is found in about 4.7∼14% of cases at autopsy. An 81-year-old man was admitted with masses in the lung, adrenal gland, bladder and colon on his CT scans. We suspected metastases of an unknown origin and we carried out EGD and colonoscopy to differentiate the primary origin of the metastases. The examination revealed a submucosal tumor-like mass with central erosion on the gastric antrum and colonic splenic flexure, and polypoid lesions with a central fissure on the second portion of the duodenum. All the endoscopic forcep biopsies showed poorly differentiated adenocarcinoma without evidence of foci of the preinvasive surface glandular lesions. Immunochemical analysis of the tumor cells showed positivity for thyroid transcription factor-1 and cytokeratin 7, and negativity for cytokeratin 20 and caudal-related homeobox 2. Therefore, we diagnosed this case as multiple gastrointestinal metastases of primary lung cancer. This is first case of gastric, duodenal and colonic metastases from adenocarcinoma of the lung in the medical literature. (Korean J Gastrointest Endosc 2010;40:102-106)
Key Words: Gastrointestinal metastases, Primary lung cancer
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