Korean J Gastrointest Endosc > Volume 40(6); 2010 > Article
Korean Journal of Gastrointestinal Endoscopy 2010;40(6): 347-351.
단일 센터에서 경험한 위장관 유암종의 임상 특성
이명희ㆍ신성재ㆍ전수진ㆍ임선교ㆍ이윤철ㆍ황재철ㆍ이기명ㆍ이광재ㆍ김진홍
아주대학교 의과대학 소화기내과학교실
Clinical Characteristics of Gastrointestinal Carcinoid Tumors
Myoung Hee Lee, M.D., Sung Jae Shin, M.D., Su Jin Jeon, M.D., Sun-Gyo Lim, M.D., Yoon Chul Lee, M.D., Jae Chul Hwang, M.D., Kee Myung Lee, M.D., Kwang Jae Lee, M.D. and Jin Hong Kim, M.D.
Department of Gastroenterology, Ajou University School of Medicine, Suwon, Korea
Abstract

Background/Aims:
Various factors have been reported that can predict the clinical course and outcome of patients with gastrointestinal (GI) carcinoid tumors. We analyzed the clinical characteristics of GI carcinoid tumors and the factors associated with metastasis.
Methods:
We retrospectively analyzed the clinical manifestations, treatment modalities and prognosis of 83 patients with GI carcinoid tumors.
Results:
The mean age of the patients was 48 years old. The locations of the carcinoid tumors were rectum (n=60), stomach (n=12), duodenum (n=6), appendix (n=4) and colon (n=1). The most common symptom was non-specific (n=65, 79.5%), and the mean tumor size was 11.2 mm. The main treatment modality was endoscopic resection (n=66, 79.5%). Nine patients showed metastasis, and all of their tumors were larger than 2 cm. Univariate analysis revealed that size, ulceration and invasion of the proper muscle layer were significant factors associated with metastasis. Tumor size (p=0.001) was the only independent factor on multivariate analysis.
Conclusions:
The diagnosis of small sized, asymptomatic GI carcinoid tumors has increased and endoscopic treatment was a useful modality. Tumor size was a predictive factor for metastasis. (Korean J Gastrointest Endosc 2010;40:347-351)
Key Words: Carcinoid tumor, Metastasis, Predictive factor
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