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Clin Endosc : Clinical Endoscopy



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HOME > Clin Endosc > Volume 41(2); 2010 > Article
A Case of Rectal Leiomyosarcoma Presenting as a Semipedunculated Polypoid Mass
[Epub ahead of print]
Published online: August 30, 2010
Department of Internal Medicine, Pusan Paik Hospital, Inje University College of Medicine, Busan, Korea
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Rectal leiomyosarcoma is an extremely rare disease. Anal bleeding, rectal pain and a sensation of pressure in the anus are the most common symptoms. It tends to form a polypoid intraluminal mass and commonly originates from the muscularis propria, but may arise from the muscularis mucosa, or in the walls of the blood vessels. Characteristically, leiomyosarcoma has very high mitotic activity and is, on immunohistochemical staining, positive for actin and desmin, but negative for c-kit and S-100. We experienced a case of a rectal leiomyosarcoma in a 54 year-old man who presented with anal bleeding. Colonoscopic examination revealed a 4.5 cm-sized semipedunculated polypoid mass at mid-rectum. We confirmed that it was a leiomyosarcoma histologically by endoscopic resection with mechanical snaring. Low anterior resection followed by radiation therapy was performed. We report here on this case with a review of the relevant literature. (Korean J Gastrointest Endosc 2010;41:118-122)

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