Korean Journal of Gastrointestinal Endoscopy 2010;41(2): 94-97.
조기 위샘암종의 부위 림프절에서 발견된 전이성 대세포 신경내분비암종
조근형ㆍ장영운ㆍ손성동ㆍ황보영ㆍ심재준ㆍ장재영ㆍ김효종ㆍ김병호
경희대학교 의과대학 내과학교실
Metastatic Large Cell Neuroendocrine Carcinoma Combined with Gastric Adenocarcinoma
Kun Hyung Cho, M.D., Young Woon Chang, M.D., Seong Dong Sohn, M.D., Young Hwangbo, M.D., Jaejun Shim, M.D., Jae Young Jang, M.D., Hyo Jong Kim, M.D. and Byung Ho Kim, M.D.
Department of Internal Medicine, College of Medicine, Kyung Hee University, Seoul, Korea
Abstract
A 67 year-old man was admitted due to findings that were suspicious for malignancy on gastroscopy at a primary clinic. We also performed gastroscopy and this showed the presence of a 3 cm sized nodular elevated lesion at the angle of the stomach. A biopsy demonstrated the presence of adenocarcinoma of the stomach. A distal gastrectomy with D2 lymph node dissection was performed and the microscopic features of the resected specimen confirmed the diagnosis of adenocarcinoma of the stomach and also metastatic large cell neuroendocrine carcinoma of lymph nodes of an unknown primary origin. Although double primary gastric adenocarcinoma and gastric neuroendocrine tumor with regional lymph node metastasis has been seldom reported, a double primary carcinoma of gastric adenocarcinoma and metastatic large cell neuroendocrine carcinoma of lymph nodes has seldom been reported. We report on this unusual case along with a review of the relevant medical literature. (Korean J Gastrointest Endosc 2010; 41:94-97)
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