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Clin Endosc : Clinical Endoscopy



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HOME > Clin Endosc > Volume 41(6); 2010 > Article
The Solitary Polypoid Ganglioneuroma of the Ascending Colon
[Epub ahead of print]
Published online: December 30, 2010
Departments of Internal Medicine and *Pathology, Yeungnam University College of Medicine, Daegu, Korea
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Ganglioneuromas are neuroectodermal tumors composed of varying amount of ganglion cells, nerve fibers, supporting cells of the enteric nervous system. Ganglioneuromas of the GI tract are rare tumors. A 50-year-old man came to our hospital due to the mass of liver and adrenal gland which was examined with ultrasonography at local medical center. On admission, abdominal magnetic resonance imaging was taken and liver biopsy was done. The mass of liver was hyperplastic nodule. At colonoscopy, about 0.3∼0.8 cm sized six polyps were noted. Except the 0.6 cm sized semipedunculated polyp of the ascending colon, the others were tubular adenomas. Histological examination of the polyp of the ascending colon revealed localized proliferation of nerve fibers and ganglion cells. These cells are positive for S-100 protein by immunihistochemistry. Therefore, he was diagnosed with polypoid ganglioneuroma of the ascending colon. We report this case because the solitary ganglioneuroma in large intestine without systemic disease was rare. (Korean J Gastrointest Endosc 2010;41:390-393)

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