| 맹장 천공과 하부위장관 출혈로 발현한 거대세포바이러스 대장염 1예 |
| 전정원ㆍ차재명ㆍ이정일ㆍ주광로ㆍ신현필ㆍ박재준ㆍ백관미ㆍ임준욱 |
| 경희대학교 의과대학 강동경희대학교병원 내과학교실 |
| Cytomegalovirus Colitis Causing Cecal Perforation and Massive Lower Gastrointestinal Bleeding |
| Jung Won Jeon, M.D., Jae Myung Cha, M.D., Joung Il Lee, M.D., Kwang Ro Joo, M.D., Hyun Phil Shin, M.D., Jae Jun Park, M.D., Kwan Mi Pack, M.D. and Jun Uk Lim, M.D. |
| Department of Internal Medicine, Gang Dong Kyung Hee University Hospital, Kyunghee University College of Medicine, Seoul, Korea |
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| Abstract |
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Cytomegalovirus (CMV) infection is associated with significant morbidity and mortality in immunocompromised patients. It may cause serious illness including bleeding, ulceration and perforation of the gastrointestinal tract. However, bowel perforation, toxic megacolon, and massive lower gastrointestinal bleeding caused by CMV in one patient is not common. In this report, we present a case of CMV colitis causing cecal perforation and massive lower gastrointestinal bleeding in a patient with lupus nephritis. In our case, severe lower gastrointestinal bleeding developed during successful treatment of CMV infection with ganciclovir. Even though the outcome of CMV colitis has improved since ganciclovir has been available for immunocompromised patients, reductions in gastrointestinal bleeding from colonic ulcers of CMV colitis may be possible during successful treatment with ganciclovir. This case suggests the possibility of lower gastrointestinal bleeding from a colon ulcer of CMV colitis should be considered during successful treatment with ganciclovir in immunocompromised patients. (Korean J Gastrointest Endosc 2011;42:33-37) |
| Key Words:
Cytomegalovirus, Colitis, Bleeding, Perforation, Ganciclovir |
| 주요어:
거대세포바이러스, 결장염, 출혈, 천공, Ganciclovir |
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