Korean Journal of Gastrointestinal Endoscopy 2011;43(1): 47-51.
대장의 아프타성 궤양 및 점막 육아종으로 발현된 Churg-Strauss 증후군 1예
박준섭ㆍ김남훈ㆍ박주현ㆍ배원기ㆍ정재원ㆍ이준성ㆍ문영수ㆍ주미*
인제대학교 의과대학 일산백병원 내과학교실, *병리학교실
A Case of Churg-Strauss Syndrome Manifesting as Colonic Aphthous Ulcers with Granuloma
Jun Sup Park, M.D., Nam-Hoon Kim, M.D., Joo Hyun Park, M.D., Won Ki Bae, M.D., Jae Won Jeong, M.D., June Sung Lee, M.D., Young Soo Moon, M.D. and Mee Joo, M.D.*
Departments of Internal Medicine and *Pathology, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Korea
Abstract
Churg-Strauss syndrome is characterized by asthma, peripheral and tissue eosinophilia, extravascular granuloma formation, and vasculitis of multiple organ systems. The gastrointestinal tract may be involved in 20% to 50% of patients, mainly with abdominal pain, diarrhea and GI bleeding. Ulcers in the small and large bowel are an uncommon manifestation, usually detected during laparotomy performed in the setting of bowel perforation. Endoscopically proven segmental colonic aphthous ulcers with typical pathologic findings such as extravascular granuloma formation, eosinophilic infiltration, or vasculitis are a rarer manifestation. We present a patient with Churg-Strauss syndrome and two aphthous ulcers in the sigmoid colon that healed after treatment with high dose steroids and cyclophosphamide. (Korean J Gastrointest Endosc 2011;43:47-51)
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