Clin Endosc > Volume 53(4); 2020 > Article
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Lee, Chung, and Kwon: Rare Cause of a Colonic Laterally Spreading Tumor

Quiz

A laterally spreading tumor was found during a screening colonoscopy in a 71-year-old woman. The lesion was flat and irregular shaped, 20 mm × 30 mm in size, and located 10 cm above the anal verge. There was no ulcer or erosion on the lesion. For histologic diagnosis and therapeutic purpose, a piecemeal endoscopic mucosal resection was performed. The endoscopic and histologic images are shown in Fig. 1.

What is the most likely diagnosis?

 

NOTES

Conflicts of Interest: The authors have no financial conflicts of interest.

Fig. 1.
Colonoscopy and microscopy findings. (A-C) Colonoscopy revealed a flat, irregularly marginated, and superficially elevated lesion at the mid-rectum for which a piecemeal endoscopic mucosal resection was performed; (D) Microscopy revealed dense lymphoid infiltration involving the mucosa and submucosa (hematoxylin and eosin, ×40).
ce-2020-197f1.jpg
Fig. 2.
Immunohistochemistry results. (A) Positive for CD20; (B) Positive for Bcl-2; (C) Negative for cyclin D1; (D) Negative for Bcl-6.
ce-2020-197f2.jpg

REFERENCES

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3. Rhee JC, Lee HY, Rhee PL, et al. [Esophagus, stomach & intestine; endoscopic findings of gastric mucosa: associated lymphoid tissue (MALT) lymphoma]. Korean J Gastrointest Endosc 1997;17:125-132.

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5. Chung CH, Kim HG, Park WS, et al. [A case of mucosa-associated lymphoid tissue lymphoma of colon as multiple large polypoid lesions]. Korean J Gastrointest Endosc 2001;23:122-126.

6. Lee YG, Lee S, Han SW, Lee JS. A case of multiple mucosa-associated lymphoid tissue (MALT) lymphoma of the colon identified as simple mucosal discoloration. J Korean Med Sci 2005;20:325-328.
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