Clin Endosc > Epub ahead of print
The Role of Endoscopy in Small Bowel Neuroendocrine Tumors
Ji Yoon Yoon , Nikhil A. Kumta , Michelle Kang Kim
Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, New York, NY, USA
Correspondence :  Ji Yoon Yoon ,Tel: +1-216-293-1249, Fax: +1-212-023-0677, Email:
Received: November 6, 2020  Revised: December 30, 2020   Accepted: December 30, 2020
Small bowel neuroendocrine tumors (NETs) represent approximately one-third of NETs of the gastrointestinal tract, and their incidence is increasing. When determining if endoscopic resection is appropriate, endoscopic ultrasound is used to assess the lesion size and depth of invasion for duodenal NETs. A number of techniques, including endoscopic mucosal resection (EMR), band-assisted EMR (band-EMR), endoscopic submucosal dissection (ESD), and over-the-scope clip-assisted endoscopic full-thickness resection (EFTR), have been studied; however, the best technique for endoscopic resection remains unclear. The vast majority of currently available data are retrospective, and prospective studies with longer follow-up times are required. For jejunal and ileal NETs, endoscopic techniques such as video capsule endoscopy (VCE) and balloon enteroscopy (BE) assist in diagnosis. This includes localization of the primary NET in metastatic disease where initial workup has been negative, and the identification of multifocal disease, which may change management and prognostication.
Key Words: Neuroendocrine tumors; Carcinoid tumors; Endoscopy; Small intestine
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