Korean Journal of Gastrointestinal Endoscopy 1995;15(3): 458-464.
원저 : 소화성 궤양 출혈의 내시경적 Hypertonic Saline - Epinephrine ( HS-E ) 용액 국소주사의 지혈효과 ( Original Articles : Hemostatic Effect of Endoscopic Injection with Hypertonic Saline - Epinephrine ( HS-E ) Solution in Petic Ulcer Bleeding )
육은주, 임의혁, 정현용, 이헌영, 김영건, 김성걸, 김진희, 서광식, 김남재 (Eun Ju Yook, Euyi Hyeog Im, Hyun Yong Jeong, Heon Young Lee, Young Kun Kim, Seong Gul Kim, Jin Hee Kim, Kwang Sik Seo and Nam Jae Kim)
Abstract
Peptic ulcer bleeding is the most common cause of upper gastromtestinal bleeding. The efficacy of local injection of hypertonic saline-epinephrine(RS-E)solutiom around the base of the bleeding vessels under endoscopy was assessed, During the period between January 1991 and August 1994, 83 patients with active bleeding or stigmata of recent hemorrhage in peptic ulcers were included to this study. The major cause of bleeding in this study consisted of gastric ulcers(60) and duodenal ulcers(23). Twenty patients rebled and seven required emergency surgery and two patients were died. Definitive hemoatasis was achieved in 74(89.3%). Two patients rebled due to mucosal ischemia induced by HS-E injection, other significant complication was not found. We conclude that the endoscopic injection with hypertonic saline-epinephrine solution is one of the effective and safe therapeutic modality in peptic ulcer bleeding.
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