Korean J Gastrointest Endosc > Volume 23(3); 2001 > Article

Korean Journal of Gastrointestinal Endoscopy 2001;23(3): 149-154.

위절제 후의 역류성 위염에서 helicobacter pylori 감염의 영향 ( Effect of Helicobacter pylori Infection on Reflux Gastritis after Gastrectomy )

손혜영(Hye Young Son),김영선(Young Sun Kim),정혜경(Hye Kyung Jung),이선영(Sun Young Yi)

Abstract

Background/Aims:
Reflux gastritis after gastrectomy is believed to be due to reflux of bile into residual stomach. However the substances that cause gastritis have not yet been precisely defined. Helicobacter pylori (H. pylori) infection is considered one of the most important pathogenetic factors in gastritis. The prevalence of H. pylori infection and the role of its infection on reflux gastritis after gastrectomy were investigated.
Methods:
Eighty-one patients who had undergone subtotal gastrectomy were enrolled. Rapid urease test and histologic examinatin for H. pylori infection were perrormed during gastrofiberacopy. An eradication of H. pylori was attempted in fifteen H. pyori-positive patients who suffered from gastritis symptoms after gastrectomy. Follow-up endoscopy was performed more than 4 weeks afrtr the end of eradication treatment.
Results:
Forty-nine patients (60.5%) demonstrated H. pylori infection in their residual stomach. The histological gastritis score in patients with H. pylori infection was significantly higher than that without infection. Ten of the 15 patients (66.7%) with H. pylori infection had their infection successfully eradicated. And also their symptoms and histological gastritis score were significantly improved.
Conclusions:
H. pylori infection does play an important role on reflux gastritis after subtotal gastrectomy. (Korean J Gastrointest Endosc 2001;23:149-154)

Key Words: H. pylori , 역류성 위염 , 위아전절제술 , Reflux gastritis , Subtotal gastrectomy