Correlation of Magnifying Endoscopy with Histology in the Gastric Mucosal Elevated Lesions

Korean J Gastrointest Endosc > Volume 26(2); 2003 > Article

Korean Journal of Gastrointestinal Endoscopy 2003;26(2): 61-67.

점막 융기성 위병변의 확대내시경 소견과 조직학적 소견의 비교

장재영·정인섭·김진오·조주영·이준성·이문성·심찬섭·김부성·진소영*

순천향대학교 의과대학 내과학교실, 소화기연구소, *임상병리학교실

Correlation of Magnifying Endoscopy with Histology in the Gastric Mucosal Elevated Lesions

Jae Young Jang, M.D., In Seop Jung, M.D., Jin Oh Kim, M.D., Joo Young Cho, M.D., Joon Seong Lee, M.D., Moon Sung Lee, M.D., Chan Sup Shim, M.D., Boo Sung Kim, M.D. and So Young Jin, M.D.*

Departments of Internal Medicine and *Pathology, Institute for Digestive Research, Soon Chun Hyang University College of Medicine, Seoul, Korea

Abstract

Background/Aims:
This is the study to clarify the relation between the mucosal patterns by magnifying endoscopy and the histologic findings in the gastric mucosal elevated lesions.
Methods:
The objectives were 51 lesions from 48 patients with gastric mucosal elevated lesions. Gastric mucosal elevated lesions have been magnified up to 80 times by using the magnifying endoscope and were obtained tissue. Magnifying mucosal patterns were classified into 6 types (dot, sulciolar, reticular, irregular, destructive and abnormal vessel pattern) and two group (Group A: dot, sulciolar, reticular pattern-preservation of mucosal arrangement, Group B: irregular, destructive, abnormal vessel pattern-destruction of mucosal arrangement). And then we compared the relation between the mucosal patterns and the histologic findings in the gastric mucosal elevated lesions.
Results:
In magnifying mucosal patterns, dot, sulciolar, reticular, irregular, destructive, and abnormal vessel pattern were 8, 5, 15, 4, 12, 7, respectively. There was significant difference in the rate of severe dysplasia or carcinoma between two groups (Group A: 0% (0/28), Group B: 70% (16/23) (p＜0.05)). The score of intestinal metaplasia and atrophy in group A were less than that of group B (p＜0.05).
Conclusions:
Irregularity, destruction and abnormal vessel formation of gastric mucosal pattern by magnifying endoscope may be suspected the histologic malignancy in the gastric mucosal elevated lesions. (Korean J Gastrointest Endosc 2003;26:61⁣67)

Key Words: Magnifying endoscopy, Gastric mucosal elevated lesions

주요어: 확대내시경, 점막 융기성 위병변