| 상부 위장관 출혈로 발현된 다발성 골수종에 병발한 식도와 위의 유전분증 1예 |
| 이상옥·이영숙·정성희·이윤정·고 훈·최기영·김안나·양현웅·차상우·김성호*·장성수† |
| 을지대학교 의과대학 내과학교실, *병리학교실, †울산대학교 의과대학 서울아산병원 진단검사의학교실 |
| A Case of Gastroesophageal Amyloidosis with Upper Gastrointestinal Bleeding in a Patient with Multiple Myeloma |
| Sang Ok Lee, M.D., Young Sook Lee, M.D., Sung Hee Jung, M.D., Yun Jung Lee, M.D., Hoon Go, M.D., Gi Young Choi, M.D., Anna Kim, M.D., Hyeon Woong Yang, M.D., Sang Woo Cha, M.D., Seong Ho Kim, M.D.* and Sung Soo Chang, M.D.† |
| Departments of Internal Medicine, *Pathology and Molecular Medicine, Eulji University School of Medicine, Eulji University Hospital, Daejeon, †Department of Laboratory Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea |
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| Abstract |
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Amyloidoses are disorders for which homogeneous amorphous fibrillar proteins accumulate in multiple organs. These diseases are classified into systemic and localized disease by their extent, the primary disease and their association with multiple myeloma, and the secondary and familial disease are classified by their association with the underlying diseases. Amyloidoses can develop in association with multiple myeloma, but only rare cases have been reported on that involve the gastroesophageal tract. Amyloidosis can involve the kidney, heart, liver, skin, gastrointestinal tract and nervous system, and they can involve the small intestine, duodenum, stomach, colon, rectum and esophagus when there is disease of the gastrointestinal tract. We may overlook gastrointestinal involvement of amyloidoses if there are few symptoms and laboratory abnormalities because of the diverse clinical courses and features. Amyloidoses can manifest abdominal pain, diarrhea, vomiting and perforation, but gastrointestinal hemorrhages are rare. We report here on a case of gastroesophageal amyloidosis with upper gastrointestinal hemorrhage and paralytic ileus due to multiple myeloma. (Korean J Gastrointest Endosc 2007;34:263268) |
| Key Words:
Amyloidosis, Multiple myeloma, Gastrointestinal hemorrhage, Stomach, Esophagus |
| 주요어:
유전분증, 다발성 골수종, 위장관 출혈, 위, 식도 |
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