| 단일기관에서 경험한 성인 위장관 Burkitt 림프종의 임상양상 |
| 정재홍ㆍ이준행ㆍ이재승ㆍ최성철ㆍ장동경ㆍ김영호ㆍ손희정ㆍ이풍렬ㆍ김재준ㆍ이종철ㆍ고영혜*ㆍ김원석 |
| 성균관대학교 의과대학 삼성서울병원 내과학교실, *병리학교실 |
| The Clinical Findings of Gastrointestinal Burkitt Lymphoma in Adults |
| Jae Hong Jung, M.D., Jun Haeng Lee, M.D., Jae Seung Lee, M.D., Sung Chul Choi, M.D., Dong Kyung Chang, M.D., Young-Ho Kim, M.D., Hee Jung Son, M.D., Poong-Lyul Rhee, M.D., Jae J. Kim, M.D., Jong Chul Rhee, M.D., Young Hyeh Ko, M.D.* and Won Seog Kim, M.D. |
| Departments of Medicine and *Pathology, Samsung Medical Center, Sungkyunkwan University College of Medicine, Seoul, Korea |
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| Abstract |
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Background/Aims:
The endoscopic and clinical findings of gastrointestinal (GI) Burkitt lymphoma in Koreans are not well known.
Methods:
From January 1995 to July 2007, 80 patients (47 adults and 33 children) were diagnosed with Burkitt lymphoma at our institution. The clinical and endoscopic manifestations were analyzed in the adult patients (n=20, median age=52 yr) with GI Burkitt lymphoma.
Results:
The most frequent symptom was abdominal pain (50%) followed by epigastic soreness (30%). Among the 20 patients with GI Burkitt lymphoma, 11 (55%) had gastric lesions, 4 (20%) had colonic lesions, 3 (15%) had both gastric and duodenal lesions, 1 (5%) had both gastric and colonic lesions, and 1 (5%) had gastric, duodenal and colonic lesions. For the 13 patients who had endoscopic pictures available, the most common type of disease was the ulcerative type (38.5%) followed by the ulcerofungating and ulceroinfiltrative types (23.1% and 23.1%, respectively). Most of the patients were diagnosed with advanced disease. The most common clinical stage was stage IVE (60%) by the Musshoff staging system. All 20 patients received combination chemotherapy, and the 5-year survival rate was 64%.
Conclusions:
For patients with GI Burkitt lymphoma, the most commonly involved site was the stomach. Most lesions were ulcerative with or without fungating morphology. Considering the advanced stage of most patients, the prognosis after systemic chemotherapy was favorable. (Korean J Gastrointest Endosc 2008;37:7-13) |
| Key Words:
Burkitt lymphoma, Gastrointestinal |
| 주요어:
Burkitt 림프종, 위장관 |
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