Korean Journal of Gastrointestinal Endoscopy 2011;43(1): 21-24.
면역기능정상 거대세포바이러스 위궤양의 항궤양제 치유
이형돈ㆍ김남훈ㆍ이기준ㆍ이혁ㆍ전진호ㆍ배원기ㆍ김경아ㆍ이준성
인제대학교 의과대학 일산백병원 내과학교실
CMV Gastric Ulcers Healed by Supportive Therapy
Hyoung Don Lee, M.D., Nam-Hoon Kim, M.D., Ki Jun Lee, M.D., Hyuk Lee, M.D., Jin Ho Jun, M.D., Won Ki Bae, M.D., Kyung-Ah Kim, M.D. and June Sung Lee, M.D.
Department of Internal Medicine, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Korea
Abstract
Cytomegalovirus (CMV) is a potentially important pathogen in an immunocompromised host. CMV infection usually occurs in patients with severe immune deficiency, such as acquired immunodeficiency syndrome, organ transplantation, malignant disease, or immunosuppressive therapy. CMV can cause ulcerations anywhere in the GI tract ranging from the esophagus to the rectum, but the colon is the most susceptible organ in the GI tract. CMV infection rarely occurs but generally causes an asymptomatic or mildly symptomatic acute illness in immunocompetent patients. Some patients with gastrointestinal CMV disease do not require antiviral treatment such as ganciclovir and frequently recover with supportive therapy. Although in immunocompetent patients, antiviral therapy may be needed based on age, chronic illness, or treatment response. We experienced a case of CMV-induced multiple gastric ulcers with severe epigastric pain in an immunocompetent patient who fully recovered with supportive therapy including a proton pump inhibitor. (Korean J Gastrointest Endosc 2011;43:21-24)
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