Korean Journal of Gastrointestinal Endoscopy 1994;14(4): 437-441.
증례 : 위정맥류에서 Histoacryl 주입으로 유발된 문맥 및 비정맥 혈전증 1예 ( Case Reports : A Case of Portal and Splenic Vein Thrombosis Developed by Complication of Histoacryl Injection Therapy in Gastric Varix )
조성원, 심찬섭, 이문성, 이준성, 이명렬, 주재학 (Sung Won Cho, Chan Sup Shim, Moon Sung Lee, Jun Sung Lee, Myung Lyel Lee and Jae Hark Ju)
Abstract
Liquid tissue adheisve, Histoacryl (n-butyl-2-cyanoacrylate) has been used for the treatment of gastric variceal bleeding. The techniques are as follows: 0.5cc Histoacryl mixed with Lipiodol per each injection are used. 3 to 4 injections are usually required for large variceal convolutes under the fluoroscopic visualization after the injection of Histoacryl. Complications of sclerotherapy with Histoacryl are bleeding, perforation, stenosis and embolism depending on the concentration and amount used, as well as the intensity of the treatment. Here we describe a case report developing portal and splenic vein thrombosis as a side effect after Histoacryl injection therapy for the treatment of gastric varix bleeding, A 59-year-old male patient with liver cirrhosis was admitted due to acute gastric varix bleeding. The control of gastrie variceal bleeding was achieved by several injections of 0.7c mixture of 0.5cc histoacryl and 0,8cc Lipiodol. However, simple X-ray and ultrasonography revealed the elements of Histoacryl-lipiodol mixture in the portal and splenic vein.
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