Korean J Gastrointest Endosc > Volume 17(2); 1997 > Article
Korean Journal of Gastrointestinal Endoscopy 1997;17(2): 167-172.
증례 : 식도 위장관 ; Menetrier 씨 병 1예 ( Case Reports : Esophagus , Stomach & Intestine ; A Case of Menetrier's Disease )
정인식, 박두호, 최상욱, 양진모, 김성수, 강성호, 남순우, 박태욱, 조돈현, 민기옥 (In Sik Chung, Doo Ho Park, Sang Wook Choi, Jin Mo Yang, Sung Soo Kim, Sung Ho Kang, Soon Woo Nam, Tae Wook Park, Don Hyoun Joe and Ki Ouk Min)
Menetrier' disease is a rare disease characterized, histologically, by epithelial hyperplasia involving the surface and foveolar mucous cells, accompanied by atrophic or normal oxyntic glands of the stomach. The 48 year-old man with epigastric discomfort and peripheral edema was admitted to St. Paul Hospital. Gastrofiberscopic examination revealed extremely thickened mucosal fold in fundus and body especially greater curvature of stomach, and microscopically there was marked hyperplasia of foveolae and cystic dilatation. Serum albumin concentration was decreased and clearance of a1-antitrypsin was markedly increased in the stool, suggesting the protein-losing enteropathy. He was diagnosed to Menetrier's disease and treated with H2 blocker, antacids, diuretics and albumin replacement.(Korean J Gastrointest Endosc 17: 167-172, 1997)
Key Words: Menetrier's disease , Protein - losing enteropathy
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