Korean Journal of Gastrointestinal Endoscopy 1999;19(4): 557-566.
위십이지장 질환자의 치태에서의 Helicobacter pylori 배양 ( Helicobacter pylori Culture in Dental Plaque of Gastroduodenal Disease Patients )
김혜랑(Hye Rang Kim),문영수(Young Soo Moon),박영숙(Young Sook Park),손향은(Hyang Eun Sohn),이주아(Joo Ah Lee),권수경(Soo Kyoung Kwon),이철우(Chul Woo Lee)
Abstract
Background/Aims: The major mode of transmission of Helicobacter pylori is still uncertain. To investigate whether the oral cavity is a potential reservoir, dental plaques were cultured from patients with dyspeptic symptoms who underwent endoscopy. Methods: Rapid urease test (CLO test), Giemsa stain, and culture were performed in 39 gastroscopic biopsy specimens from patients with peptic ulcer, chronic gastritis or gastric cancer. Ten gastric mucosal biopsy specimens and 39 dental plaque specimens were innoculated onto 5% sheep blood agar. Results: Twenty patients (51%) were found to be H. pylori positive on antral histology or rapid urease test. Among ten patients, 8 patients (80%) were cultured for H. pylori from antral biopsies. However H. pylori was not isolated from any dental plaque regardless of their infective status and their oral hygiene or gingival status. Conclusions: We failed to isolate H. pylori from dental plaques in a group of dyspeptic patients with H. pylori-associated gastroduodenal disease. The findings strongly suggest that dental plaque is not an important reservoir of H. pylori and probably not a significant factor in the mode of transmission of H. pylori. (Korean J Gastrointest Endosc 19: 557∼566, 1999)
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