Korean Journal of Gastrointestinal Endoscopy 2000;21(5): 844-848.
시사프라이드의 대장내시경 전처치 용액의 감량 효과 ( The Effects of Cisapride on Volume of Colonoscopy Lavage Solution )
박찬원(Chan Won Park),박정호(Jung Ho Park),권정훈(Jung Hun Gwan),조대현(Dae Hyun Jo),이홍석(Hong Suk Lee),이성호(Sung Ho Lee),김현수(Hyun Soo Kim),김현서(Hyun Seo Kim),이현택(Hyun Taek Lee),장재권(Jae Gwan Jang),심상군(Sang Goon Shim),성인경(In Gyung Sung)
Abstract
Background/Aims: Polyethylene glycol (PEG) electrolyte lavage solution is now commonly used for peroral colonic preparation. However, the need to ingest a large volume reduces patient acceptance and may limit compliance, thereby resulting in improper preparation. This study was designed to assess whether adding of magnesium oxide or cisapride to PEG solution decreased the volume of PEG solution required without compromising the quality of the preparation. Methods: One hundred thirty seven patients undergoing outpatient colonoscopy were randomly chosen to receive one of three preparations (Group A: 4 L PEG; Group B: 2 L PEG plus cisapride 20 mg; Group C: 2 L PEG plus magnesium oxide 2 g). Endoscopist was blinded as to the method of preparation and scored the degree of colonic preparation (1 to 4). Results: Mean scores of preparation in group A, B, and C were 2.85, 2.69, and 2.20, respectively (p=0.001). There were significant differences of the degree of preparation between group A and group C, between group B and group C, but not between group A and group B. Conclusions: Two liters of PEG plus cisapride induced equally effective colonic preparation compared to four liter PEG solution. This results show that the addition of cisapride to PEG solution can reduce volume of PEG solution during colonoscopy preparation.
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