Korean J Gastrointest Endosc > Volume 20(1); 2000 > Article
Korean Journal of Gastrointestinal Endoscopy 2000;20(1): 33-40.
췌장의 점액 생산성 종양과 유사한 점액 생산성 담도암 8예 ( Eight Cases of Mucin-hypersecreting Cholangiocarcinoma Similar to Intraductal Papillary Mucinous Tumor of the Pancreas )
장혜숙(Hye Sook Chang),김홍자(Hong Ja Kim),나주옥(Joo Ock Na),임병철(Byung Cheol Lim),유교상(Kyo Sang Yoo),박은택(Eun Taek Park),서동완(Dong Wan Seo),이성구(Sung Koo Lee),김명환(Myung Hwan Kim),민영일(Young Il Min)

Mucin-hypersecreting cholangiocarcinoma is very similar to intraductal papillary mucinous tumor (IPMT) of the pancreas. But this disease is rare and its clinicopathologic features are not well known. The purposes of this study are to report our experience of eight patients with the tumor and to analyze the characteristics of its clinical, radiological and pathological finding.
Eight patients (3 men and 5 women, mean age 52 years) were diagnosed as having a mucin-hypersecreting cholangiocarcinoma among 4,570 cases of ERCP from 1995 to 1998.
Recent or previous attacks of biliary pain or acute cholangitis were elicited in most of the patients. CT showed diffuse intra- and extra-hepatic duct dilatation in all patients and suspicious ill-defined mass shadow in 2 out of 8 patients. On cholangioscopic examination, a papillary mass or minute mucosal lesion was found in the dilated bile duct containing thick viscid mucin. Eight patients were recommended an operation and curative resection was performed in seven patients. Histologically, well-differentiated adenocarcinoma in the background of benign hyperplasia and adenoma was documented in all patients.
Mucin- hypersecreting cholangiocarcinoma may be characterized by exceedingly similarity to IMPT of the pancreas in clinical, radiological and pathological features. Further investigation is needed for detailed information such as natural history and outcome. (Korean J Gastrointest Endosc 2000;20:33~40)
Key Words: Mucin-hypersecreting cholangiocarcinoma, Pancreas, IPMT
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