Korean Journal of Gastrointestinal Endoscopy 2011;42(6): 428-432.
Two Cases of Xanthogranulomatous Cholecystitis and Gallbladder
Cancer with Hemobilia
Jong Kyu Kwon, M.D., Dae Jin Kim, M.D., Hyun Uk Ryu, M.D., Soo Hwan Seol, M.D., Byung Sik Hwang, M.D.,
Jong Hun Park, M.D.* and Kyung Rak Son, M.D.†
Departments of Internal Medicine, *Surgery and †Pathology, Daegu Fatima Hospital, Daegu, Korea
Abstract
Hemobilia is a rare upper gastrointestinal (GI) bleeding phenomenon usually
caused by trauma but may occur due to various liver and pancreatobiliary diseases.
Causes related to gallbladder disease include vascular disorders, malignancy,
polyps, heterotopic GI mucosa, acalculous inflammation, and most commonly
gallstones. Most cases are treated with a cholecystectomy. If hemobilia is detected,
efforts must be made to exclude malignancy because hemobilia develops from both
benign and malignant disease. Particularly in gallbladder disease with hemobilia,
the possibility of gallbladder carcinoma should be considered. We report two cases
of hemoblia by endoscopic retrograde cholangiopancreatography and duodenoscopy,
with a review of the literature. The first case was xanthoglanulomatous
cholesystitis and the second case was gallbladder cancer disclosed by cholecystectomy.
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