Korean J Gastrointest Endosc > Volume 27(2); 2003 > Article
Korean Journal of Gastrointestinal Endoscopy 2003;27(2): 57-63.
상부 위장관 출혈 환자의 임상적 고찰 및 소화성 궤양 출혈 환자에서 조기 재출혈의 위험인자 분석
박현용⋅허진욱⋅최바울⋅박남영⋅김지연⋅김동완
고신대학교 의과대학 내과학교실
Clinical Findings of Upper Gastrointestinal Bleeding and Risk Factors for Early Rebleeding in Patients with Bleeding Peptic Ulcers
Hyeon Yong Park, M.D., Jin Wook Hur, M.D., Paul Choi, M.D., Nam Young Park, M.D., Jee Yeon Kim, M.D., Dong Wan Kim, M.D., Jee Young Lee, M.D., Ki Hwan Kim, M.D., Moo In Park, M.D., Seun Ja Park, M.D. and Ja Young Koo, M.D.
Department of Internal Medicine, Kosin University College of Medicine, Busan, Korea
Abstract

Background/Aims:
Upper gastrointestinal (UGI) bleeding may have serious complications. Endoscopic therapy is effective in the hemostasis of active bleeding. We analysed the causes of UGI bleeding and evaluated risk factors and rate of rebleeding in patients with bleeding peptic ulcer.
Methods:
Records from 326 patients admitted with upper gastrointestinal bleeding between January 1998 and December 2002 were reviewed. We retrospectively analyzed clinical findings and rebleeding risk factors of peptic ulcers.
Results:
Common causes of UGI bleeding were esophageal varix (38.0%), peptic ulcer (36.9%), Mallory-Weiss tear (13.8%), stomach cancer (6.4%). Early rebleeding of bleeding peptic ulcer after hemostasis occurred in 23 cases (19.2%). On the basis of univariate analysis, significant predictive factors for early rebleeding were old age (>65) (p=0.034), size of ulcer (>2 cm) (p=0.002), number of ulcer (>1) (p=0.059). In multivariate analysis, old age (odds ratio, OR=2.3), size of ulcer (OR=3.3), number of ulcer (OR=2.6) were independent risk factors of rebleeding.
Conclusions:
Common causes of UGI bleeding are esophageal varix, peptic ulcer, Mallory-Weiss tear. Predictive risk factors for early rebleeding in bleeding peptic ulcer may be old age, size of ulcer and number of ulcer. (Korean J Gastrointest Endosc 2003;27:57⁣63)
Key Words: Upper gastrointestinal bleeding, Peptic ulcer, Endoscopic therapy, Early rebleeding
주요어: 상부 위장관 출혈, 소화성궤양, 내시경적 지혈술, 조기 재출혈
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