Korean J Gastrointest Endosc > Volume 29(6); 2004 > Article
Korean Journal of Gastrointestinal Endoscopy 2004;29(6): 524-528.
대장 결핵과 동반된 미만성 침윤성 대장암 1예
이화여자대학교 의과대학 내과학교실, *병리학교실
A Case of Diffuse Infiltrative Colon Cancer Coexisting with Colonic Tuberculosis
Chang Yoon Ha, M.D., Hye-Kyung Jung, M.D., Jung Hwa Ryu, M.D., Hae Sun Jung, M.D., Gun Woo Pyun, M.D., Doe Young Kim, M.D., Il Hwan Moon, M.D. and Min-Sun Cho, M.D.*
Departments of Internal Medicine and *Pathology, Ewha Womans University College of Medicine, Seoul, Korea
Inflammatory bowel disease has a potential risk of developing colorectal cancer. However, there is little causal relationship between intestinal tuberculosis and colon cancer because intestinal tuberculosis is curable disease and has relatively short disease course. But there were a few case reports of intestinal tuberculosis associated with colon cancer. Diffuse infiltrating colon cancer, characterized by tumor cells in the presence of inflammatory changes with much fibrosis, is very rare in the colon. We experienced a 49-year-old woman who had tuberculous colitis combined with diffuse infiltrative colon cancer. She visited our hospital because of chronic diarrhea and abdominal pain. Colonoscopy showed multiple geographic ulcers in the transverse colon and partial intestinal obstruction. Histological examination revealed non-caseating granuloma and Mycobacterium tuberculosis was cultured in biopsied tissue. She took an anti- tuberculosis drug for 2 weeks, but her symptoms were aggravated. Therefore, extended right hemicolectomy was performed and revealed mucin-secreting, diffuse infiltrating adenocarcinoma. Herein, we report a rare case of diffuse infiltrative colon cancer coexisting with colonic tuberculosis with a review of liferatures. (Korean J Gastrointest Endosc 2004;29:524⁣528)
Key Words: Colon cancer, Colonic tuberculosis, Diffuse infiltrating cancer
주요어: 대장결핵, 대장암, 미만성 침윤암
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