Center for Gastric Cancer, National Cancer Center, Goyang, Korea
Copyright © 2019 Korean Society of Gastrointestinal Endoscopy
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Study |
Depth |
Size |
Lymphovascular invasion |
||||||
---|---|---|---|---|---|---|---|---|---|
Mucosa | Submucosa | OR | ≤2 cm | >2 cm | OR | Absent | Present | OR | |
Hirasawa et al. (2009) [9] | 4.9% (105/2,163) | 23.8% (399/1,680) | 3.2 | 7.0% (77/1,107) | 15.6% (427/2,736) | 2.05 | 7.6% (249/3,266) | 44.2% (255/577) | 4.82 |
Kunisaki et al. (2009) [10] | 2.2% (6/269) | 11.0% (13/118)a) | 2.9 | 4.7% (7/149) | 15.8% (67/424) | 3.3 | 4.5% (20/446) | 42.5% (54/127) | 9.4 |
Ye et al. (2008) [8] | 2.9% (10/339) | 11/8% (6/51)b) | 2.6 | 2.7% (5/182)c) | 18.1% (74/409) | 5.7 | 6.7% (35/520) | 62.0% (44/71) | 5.5 |
Li et al. (2008) [11] | 4.2% (15/356) | 15.9% (46/290) | 2.8 | 6.7% (24/360) | 12.9% (37/286) | 2.0 | 6.0% (36/601) | 55.6% (25/45) | 15.1 |
Study | Frequency | 95% CI |
---|---|---|
Gotoda et al. (2000) [5] | 0% (0/141) | 0%–2.6% |
Hirasawa et al. (2009) [9] | 0% (0/310) | 0%–0.96% |
Kunisaki et al. (2009) [10] | 0% (0/84) | - |
Ye et al. (2008) [8] | 0% (0/119)b) | - |
Li et al. (2008) [11] | 0.5% (1/201)c) | - |
Chung et al. (2011) [7] | 1.1% (3/261) | 0%–2.4% |
Study | Curative resection | Tumor size | Depth | LVI | Ulcer |
---|---|---|---|---|---|
Ahn et al. (2016) [15] | 70.3% (71/101) | 16.8% (17/101) | 8.9% (9/101) | 4.0% (4/101) | - |
Oka et al. (2014) [14] | 64.8% (81/125) | 12.8% (16/125) | 22.4% (28/125) | 4.8% (6/125) | 8.8% (11/125) |
Abe et al. (2013) [12] | 63.9% (62/97) | 14.4% (14/97) | 19.6% (19/97) | 3.1% (3/97) | 9.3% (9/97) |
Study | Differentiated-type | Signet ring cell type | Other undifferentiated-typea) |
---|---|---|---|
Kwon et al. (2014) [34] | 11.7% (24/205) | 9.8% (5/51) | 17.1% (12/70) |
Kim et al. (2014) [35] | 9.4% (99/1,024) | 9.0% (31/345) | 18.1% (118/651) |
Ha et al. (2008) [36] | 8.2% (72/879) | 9.5% (37/388) | 24.9% (63/253) |
Tong et al. (2011) [37] | 14.0% (32/229) | 14.7% (15/102) | 34.1% (31/91) |
Guo et al. (2015) [38] | 9.8% (34/347) | 13.1% (26/198) | 23.8% (124/522) |
Study | Depth |
Size |
Lymphovascular invasion |
||||||
---|---|---|---|---|---|---|---|---|---|
Mucosa | Submucosa | OR | ≤2 cm | >2 cm | OR | Absent | Present | OR | |
Hirasawa et al. (2009) [9] | 4.9% (105/2,163) | 23.8% (399/1,680) | 3.2 | 7.0% (77/1,107) | 15.6% (427/2,736) | 2.05 | 7.6% (249/3,266) | 44.2% (255/577) | 4.82 |
Kunisaki et al. (2009) [10] | 2.2% (6/269) | 11.0% (13/118) |
2.9 | 4.7% (7/149) | 15.8% (67/424) | 3.3 | 4.5% (20/446) | 42.5% (54/127) | 9.4 |
Ye et al. (2008) [8] | 2.9% (10/339) | 11/8% (6/51) |
2.6 | 2.7% (5/182) |
18.1% (74/409) | 5.7 | 6.7% (35/520) | 62.0% (44/71) | 5.5 |
Li et al. (2008) [11] | 4.2% (15/356) | 15.9% (46/290) | 2.8 | 6.7% (24/360) | 12.9% (37/286) | 2.0 | 6.0% (36/601) | 55.6% (25/45) | 15.1 |
Study | Frequency | 95% CI |
---|---|---|
Gotoda et al. (2000) [5] | 0% (0/141) | 0%–2.6% |
Hirasawa et al. (2009) [9] | 0% (0/310) | 0%–0.96% |
Kunisaki et al. (2009) [10] | 0% (0/84) | - |
Ye et al. (2008) [8] | 0% (0/119) |
- |
Li et al. (2008) [11] | 0.5% (1/201) |
- |
Chung et al. (2011) [7] | 1.1% (3/261) | 0%–2.4% |
Study | Curative resection | Tumor size | Depth | LVI | Ulcer |
---|---|---|---|---|---|
Ahn et al. (2016) [15] | 70.3% (71/101) | 16.8% (17/101) | 8.9% (9/101) | 4.0% (4/101) | - |
Oka et al. (2014) [14] | 64.8% (81/125) | 12.8% (16/125) | 22.4% (28/125) | 4.8% (6/125) | 8.8% (11/125) |
Abe et al. (2013) [12] | 63.9% (62/97) | 14.4% (14/97) | 19.6% (19/97) | 3.1% (3/97) | 9.3% (9/97) |
Study | Differentiated-type | Signet ring cell type | Other undifferentiated-type |
---|---|---|---|
Kwon et al. (2014) [34] | 11.7% (24/205) | 9.8% (5/51) | 17.1% (12/70) |
Kim et al. (2014) [35] | 9.4% (99/1,024) | 9.0% (31/345) | 18.1% (118/651) |
Ha et al. (2008) [36] | 8.2% (72/879) | 9.5% (37/388) | 24.9% (63/253) |
Tong et al. (2011) [37] | 14.0% (32/229) | 14.7% (15/102) | 34.1% (31/91) |
Guo et al. (2015) [38] | 9.8% (34/347) | 13.1% (26/198) | 23.8% (124/522) |
EGC, early gastric cancer; OR, odds ratio. SM 1 (<500 um). SM 1/3 (upper third of the submucosa). Size ≤2.5 cm, >2.5 cm.
CI, confidence interval. Curative resection criteria: confined to the mucosa, lymphovascular invasion negative, ulcer negative, and size ≤2 cm. Size ≤2.5 cm. Ulcer was not evaluated.
ESD, endoscopic submucosal dissection; LVI, lymphovascular invasion.
EGC, early gastric cancer. Poorly differentiated tubular adenocarcinoma or non-signet ring cell poorly cohesive carcinoma.