Korean Journal of Gastrointestinal Endoscopy 1992;12(1): 53-56.
위암과 동반된 Leiomyomatosis Peritonealis Disseminata 1예 ( A Case of Leimyomatosis Peritonealis Disseminata Combined with Advanced Gastric Cancer )
박승우, 김원호, 강진경, 박인서, 최흥재, 김충배, 전용찬, 박찬일 (Seung Woo Park, Won Ho Kim, Jin Kyung Kang, In Suh Park, Heung Jai Choi, Yong Chan Chun and Chan Il Park)
Abstract
Leiomyomatosis peritonealis disseminata is a rare benign condition characterised by the occurrence of multiple leimyomas scatterred throughout the peritoneal cavity, giving the clinical impression of a wide spread malignant tumor. The histopathology of leiomyomatosis peritonealis disseminata is that of a benign leiomyoma, probably originating from the multipotent subcoelomic mesenchymal cells. Three cases with malignant transformation were described among previous reported fifty cases. Many of the early reports described the disorder in premenopausal women, and now the histogenesis is considered to be a metaplastic change by abnormal tissue response to the relatively or absolutely elevated female sex hormone. We report a case of leiomyomatosis peritonealis disseminata, which was diagnosed by multiple scattered submucosal and subseroal leimyomas of stomach, small bowel and colon, combined with advanced gastric cancer in a 58 years old man, Multiple submucosal tumors of the stomach combined with advanced gastric cancer were demonstrated by fibergastroscopy, upper gastrointestinal barium study and abdominal ultrasonography. During radical subtotal gastrectomy multiple submucosal and subserosal tumors of stomach, and subserosal tumors of small bowel and colon were observed and these tumors were confirmed as leiomyoma without malignant potential.
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