Korean J Gastrointest Endosc > Volume 36(1); 2008 > Article
Korean Journal of Gastrointestinal Endoscopy 2008;36(1): 22-26.
위분문부에 위치한 과립세포종 1예
부산대학교 의학전문대학원 내과학교실
A Granular Cell Tumor Located in the Gastric Cardia
Jin Sup Park, M.D., Gwang Ha Kim, M.D., Mi Ra Kim, M.D., Hong Ryul Jeong, M.D., Jae Hoon Cheong, M.D., Chan Ho Park, M.D., Sun Mi Lee, M.D., Tae Oh Kim, M.D., Jeong Heo, M.D., Dae Hwan Kang, M.D., Geun Am Song, M.D. and Mong Cho, M.D.
Department of Internal Medicine, Pusan National University School of Medicine, Busan, Korea
First described in 1926 by Abrikossoff, a granular cell tumor is a benign lesion and commonly involves the skin, connective tissue, and breast, but rarely the esophagus. The origin of granular cell tumors is controversial. The tumor is thought to arise from a Schwann cell origin, based on characteristics such as the positive expression of S-100 protein determined by immunohistochemical staining. A 29-year-old female was referred from the local clinic because of a polypoid lesion in the gastric cardia. After performing endoscopy and endoscopic ultrasonography, a 1.5 cm submucosal tumor covered with normal mucosa was found in the gastric cardia. Endoscopic mucosal resection revealed a tumor that initiated in the esophagus, and grew into the cardia. Immunohistochemical analysis revealed strong positive staining for S-100 protein, confirming the presence of a granular cell tumor. (Korean J Gastrointest Endosc 2008;36:22-26)
Key Words: Granular cell tumor, Gastric cardia, Endoscopic mucosal resection
주요어: 과립세포종, 위분문부, 내시경 점막절제술
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